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1-Methylguanidine hydrochloride

1-Methylguanidine hydrochloride

In vial of 1 g net

TargetMol Chemicals Inc.

Product Overview

Product / Grade Name

1-Methylguanidine hydrochloride

Product Description

Methylguanidine (MG) is a guanidine compound deriving from protein catabolism. It is also a product of putrefaction. Methylguanidine is a suspected uraemic toxin that accumulates in renal failure, however it also exhibits anti-inflammatory effects. Methylguanidine is synthesized from creatinine concomitant with the synthesis of hydrogen peroxide from endogenous substrates in peroxisomes. Recent evidence suggests that methylguanidine significantly inhibits iNOS activity and TNF- release. This means that methylguandine can attenuate the degree of inflammation and tissue damage associated with endotoxic shock.

Hazard Classification

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