5-Hydroxymethyl-2'-deoxycytidine
In vial of 0.5 g net
TargetMol Chemicals Inc.
Product Overview
Product / Grade Name
5-Hydroxymethyl-2'-deoxycytidine
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Product Description
5-Hydroxymethyl-2'-deoxycytidine is an oxidized derivative of 5-methyl-2'-deoxycytidine (5-mdC) in DNA, causing DNA damage reactions, chromosomal aberrations, replication fork damage, and loss of cell viability.5-Hydroxymethyl-2'-deoxycytidine is an oxidized derivative of 5-methyl-2'-deoxycytidine in DNA. Hydroxymethyl-2'-deoxycytidine replication fork instability is associated with the presence of poly(ADP-ribose) polymerase 1 (PARP1) on chromatin.
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