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7-Chlorokynurenic acid

7-Chlorokynurenic acid

In vial of 0.5 g net

TargetMol Chemicals Inc.

Product Overview

Product / Grade Name

7-Chlorokynurenic acid

Product Description

7-Chlorokynurenic acid (7-chloro-4-hydroxy-2-carboxyquinoline) is an effecitve and selective antagonist of NMDA receptor with IC50 of 0.56 μM for the glycine B coagonist site. 7-Chlorokynurenic acid inhibits the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM and shows antinociceptive actions after neuraxial delivery.

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