Bosentan
In vial of 0.5 g net
TargetMol Chemicals Inc.
Product Overview
Product / Grade Name
Bosentan
Maker Name
Product Description
Bosentan (Benzenesulfonamide) is a sulfonamide-derived, competitive and specific endothelin receptor antagonist with a slightly higher affinity for the endothelin A receptor than endothelin B receptor. Bosentan blocks the action of endothelin 1, an extremely potent endogenous vasoconstrictor and bronchoconstrictor, by binding to endothelin A and endothelin B receptors in the endothelium and vascular smooth muscle. Bosentan decreases both pulmonary and systemic vascular resistance and is particularly used in the treatment of pulmonary arterial hypertension.
Hazard Classification
UN Number
:IMGD Class
:Packing Group
:
Visual Overview
Corporate Video