Brevilin A
In vial of 0.5 g net
TargetMol Chemicals Inc.
Product Overview
Product / Grade Name
Brevilin A
Maker Name
Product Description
Brevilin A is a sesquiterpene lactone isolated from Centipeda minima, inhibits janus kinase activity and blocks STAT3 signaling in cancer cells with anti-tumor activity. Brevilin A is a selective inhibitor of JAK-STAT signal pathway by attenuating the JAKs activity and blocking STAT3 signaling (IC50 = 10.6 μM) in Cancer Cells.Brevilin A induces apoptosis and autophagy via mitochondrial pathway and PI3K/AKT/mTOR inactivation in colon adenocarcinoma cell CT26.antitumour
Hazard Classification
UN Number
:IMGD Class
:Packing Group
:
Visual Overview
Corporate Video