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Buclizine dihydrochloride

Buclizine dihydrochloride

In vial of 1 g net

TargetMol Chemicals Inc.

Product Overview

Product / Grade Name

Buclizine dihydrochloride

Product Description

Buclizine dihydrochloride (Buclina) is the hydrochloride salt form of buclizine, a piperazine histamine H1 receptor antagonist with primarily antiemetic and antivertigo activities. Buclizine dihydrochloride binds to and blocks the histamine H1 receptor, thereby preventing the symptoms that are caused by histamine activity. Buclizine dihydrochloride exerts its anti-emetic effect by binding to and blocking the muscarinic and histamine receptors in the vomiting center of the central nervous system (CNS). This may prevent activation of the chemoreceptor trigger zone (CTZ) and may reduce nausea and vomiting.

Hazard Classification

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Visual Overview

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