CDDO-dhTFEA
In vial of 0.5 g net
TargetMol Chemicals Inc.
Product Overview
Product / Grade Name
CDDO-dhTFEA
Maker Name
Product Description
CDDO-dhTFEA, a synthetic oleanane triterpenoid, effectively activates Nrf2 while inhibiting the NF-κB pro-inflammatory transcription factor. It restores mean arterial pressure (MAP), elevates Nrf2 levels and the expression of related genes, attenuates NF-κB and transforming growth factor-β pathway activation, and mitigates glomerulosclerosis, interstitial fibrosis, and inflammation in rats with chronic kidney disease (CKD).
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Visual Overview
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