Capmatinib 2HCl
In vial of 0.5 g net
TargetMol Chemicals Inc.
Product Overview
Product / Grade Name
Capmatinib 2HCl
Maker Name
Product Description
Capmatinib 2HCl (INC-280 2HCl) is a novel, ATP-competitive inhibitor of c-MET kinase with an IC50 with 0.13 nM.Capmatinib 2HCl exhibits picomolar enzymatic potency and is highly specific for c-MET with more than 10, 000-fold selectivity over a large panel of human kinases. This inhibitor potently blocks c-MET phosphorylation and activation of its key downstream effectors in c-MET-dependent tumor cell lines. As a result, Capmatinib 2HCl potently inhibits c-MET-dependent tumor cell proliferation and migration and effectively induces apoptosis in vitro.
Hazard Classification
UN Number
:IMGD Class
:Packing Group
:
Visual Overview
Corporate Video