Carbamazepine 10,11-epoxide
In vial of 0.5 g net
TargetMol Chemicals Inc.
Product Overview
Product / Grade Name
Carbamazepine 10,11-epoxide
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Product Description
Carbamazepine 10,11-epoxide is an active metabolite of the anticonvulsant carbamazepine. It is formed by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP2C8 in microsomes from HepG2 cells expressing CYP3A4 or CYP2C8, respectively. Carbamazepine 10,11-epoxide exhibits anticonvulsant activity against maximal electroshock-induced seizures in mice and has been detected in wastewater effluent [1][2][3].
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