
Endoxifen
In vial of 0.5 g net
TargetMol Chemicals Inc.
Product Overview
Product / Grade Name
Endoxifen
Maker Name
Product Description
(E/Z)-Endoxifen ((E/Z)-Endoxifen) is an active metabolite of tamoxifen produced by the sequential action of cytochrome P450 (CYP) isoforms, including CYP2D6. It is a strong anti-estrogen, as it has an approximately 100-fold greater affinity for estrogen receptors than tamoxifen. As the efficient conversion of tamoxifen to endoxifen depends on CYP2D6, polymorphisms in this CYP isoform can impact the effectiveness of TMX treatment.
Hazard Classification
UN Number
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Visual Overview
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