JI6

In vial of 0.5 g net

TargetMol Chemicals Inc.

Product Overview

Product / Grade Name

JI6

Product Description

JI6 (JAK3 Inhibitor VI) is a potent, selective and orally active FLT3 inhibitor. JI6 exhibits IC50s of ?40, 8, and 4 nM for FLT3-WT, FLT3-D835Y, and FLT3-D835H, respectively. JI6 also inhibits c-Kit and JAK3, with IC50s of ?500 and ?250 nM, respectively. JI6 has research value in acute myeloid leukemia.

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Visual Overview

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