Jervine
In vial of 0.5 g net
TargetMol Chemicals Inc.
Product Overview
Product / Grade Name
Jervine
Maker Name
Product Description
The biological activity of Jervine (Jerwiny) is mediated via its interaction with the 7 passes transmembrane protein Smoothened. Jervine binds with and inhibits smoothened, which is an integral part of the Hedgehog signaling pathways. With smoothened inhibited, the GLI1 transcription cannot be activated and Hedgehog target genes cannot be transcribed.
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