
LTβR-IN-1
In vial of 0.5 g. net
TargetMol Chemicals Inc.
Product Overview
Product / Grade Name
LTβR-IN-1
Maker Name
Product Description
LTβR-IN-1 is a potent and selective lymphin β receptor (LTβR) inhibitor with a selective inhibitory effect on the nuclear translocation of p52 of TNF12A, without affecting the nuclear translocation of p65 mediated by the TNF-α receptor. It inhibits p52 nuclear translocation stimulated by TWEAK or Anti-LTβR with an IC50 of 10 μM and regulates the NF-kB signaling pathway in a ligand-independent manner.
Hazard Classification
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Visual Overview
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