NRX-252114
In vial of 0.5 g. net
TargetMol Chemicals Inc.
Product Overview
Product / Grade Name
NRX-252114
Maker Name
Product Description
NRX-252114 (NRX252114) induces degradation of mutant β-catenin NRX-252114 is a potent enhancer of the interaction of β-catenin with the homologous E3 ligase SCFβ-TrCP, and is able to enhance the binding of pSer33/S37A β-catenin to β-TrCP with an EC50 of 6.5 nM and a Kd of 0.4 nM. Kd is 0.4 nM.
Hazard Classification
UN Number
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Visual Overview
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