PF-6274484

In vial of 0.5 g. net

TargetMol Chemicals Inc.

Product Overview

Product / Grade Name

PF-6274484

Product Description

PF-6274484, a high affinity, irreversible covalent inhibitor of EGFR kinase with Ki of 0.14 nM, inhibits the autophosphorylation of wild-type EGFR in A549 cells and EGFRL858R/T790M in H1975 cells with IC50 of 5.8 nM and 6.6 nM, respectively.

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Visual Overview

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