PF-915275
In vial of 0.5 g. net
TargetMol Chemicals Inc.
Product Overview
Product / Grade Name
PF-915275
Maker Name
Product Description
PF-915275 is an effective and selective inhibitor of human 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1, Ki = 2.3 nM, EC50 = 15 nM in vitro HEK293 cells). The dose-dependent effect of PF-915275 on conversion of cortisone to cortisol in primary human and monkey hepatocytes, with an EC50 of 20 and 100 nM, respectively.
Hazard Classification
UN Number
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Visual Overview
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