Rofecoxib
In vial of 0.5 g. net
TargetMol Chemicals Inc.
Product Overview
Product / Grade Name
Rofecoxib
Maker Name
Product Description
Rofecoxib (MK 966) binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in an inhibition of the conversion of arachidonic acid to prostaglandins. Rofecoxib is a synthetic, nonsteroidal derivative of phenyl-furanone with anti-inflammatory, antipyretic and analgesic properties and potential antineoplastic properties. COX-related metabolic pathways may represent key regulators of cell proliferation and neo-angiogenesis. Some epithelial tumor cell types overexpress pro-angiogenic COX-2.
Hazard Classification
UN Number
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Visual Overview
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